Environmental Causes of Esophageal Cancer

Combating environmental causes of cancer.

791 each agent with the control. The ability to test multiple therapies in a smaller population will become more important as disease subcategories are increasingly defined by specific phenotypic, biologic, and genetic markers, and the available number of patients in a given category becomes a limiting factor in conducting relevant studies. The collaborative trial approach permits direct evalua...

Environmental and Occupational Causes of Cancer

Occupational and environmental causes of lung cancer.

Because tobacco smoking is a potent carcinogen, secondary causes of lung cancer are often diminished in perceived importance. The goal of this review is to describe the occurrence and recent findings of the 27 agents currently listed by the International Agency for Research on Cancer (IARC) as lung carcinogens. The IARC's updated assessments of lung carcinogens provide a long-overdue resource f...

Attributable Causes of Esophageal Cancer Incidence and Mortality in China

BACKGROUND To estimate the contribution of tobacco smoking, alcohol drinking, low vegetable intake and low fruit intake to esophageal cancer mortality and incidence in China. METHODOLOGY/PRINCIPAL FINDINGS We calculated the proportion of esophageal cancer attributable to four known modifiable risk factors [population attributable fraction (PAF)]. Exposure data was taken from meta-analyses and...

Environmental and occupational causes of cancer re-visited.

We recently completed a review of scientific evidence, particularly epidemiologic evidence, regarding the contribution of environmental and occupational exposures to the overall cancer burden in the US. We evaluated the efforts to estimate the proportion of cancer due to these involuntary exposures, including the ambitious effort by Doll and Peto and an update by a group of authors at the Harva...